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The enhancing effect and promoting mechanisms of the stereoisomeric monoterpene alcohol esters as enhancers for drugs with different physicochemical properties

To explore the structure-activity connections of amphiphilic permeation enhancers containing the length of the hydrophobic chains as well as the properties of the polar head, O-acylgeraniol and O-acylnerol derivatives were synthesized from geraniol/nerol (cis-isomer of geraniol) and pharmaceutical e...

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Detalles Bibliográficos
Autores principales: Wang, Heping, Li, Yan, Wang, Chunyan, Wang, Jing, Ren, Bo, Li, Xiaona, Li, Mingzhu, Geng, Dandan, Wu, Chensi, Zhao, Ligang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888174/
https://www.ncbi.nlm.nih.gov/pubmed/35261650
http://dx.doi.org/10.1016/j.ajps.2021.11.003