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Sodium alginate and naloxone loaded macrophage-derived nanovesicles for the treatment of spinal cord injury

Spinal cord injury (SCI) causes Ca(2+) overload, which can lead to inflammation and neuronal apoptosis. In this study, we prepared a nanovesicle derived from macrophage membrane (MVs), which encapsulated sodium alginate (SA) and naloxone (NAL) to inhibit inflammation and protect neurons by reducing...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoyao, Jiang, Xue, Yu, Qi, Shen, Wenwen, Tian, He, Mei, Xifan, Wu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888181/
https://www.ncbi.nlm.nih.gov/pubmed/35261646
http://dx.doi.org/10.1016/j.ajps.2021.11.001