Assessment of dermal bioavailability: predicting the input function for topical glucocorticoids using stratum corneum sampling

Predicting the dermal bioavailability of topically delivered drugs is challenging. In this work, minimally invasive stratum corneum (SC) sampling was used to quantify the delivery of betamethasone valerate (BMV) into the viable skin. Betnovate® cream (0.1% w/w BMV) was applied at three doses (2, 5,...

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Detalles Bibliográficos
Autores principales: Pensado, Andrea, McGrogan, Anita, White, K. A. Jane, Bunge, Annette L., Guy, Richard H., Delgado-Charro, M. Begoña
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888398/
https://www.ncbi.nlm.nih.gov/pubmed/34599470
http://dx.doi.org/10.1007/s13346-021-01064-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888398/
https://www.ncbi.nlm.nih.gov/pubmed/34599470
http://dx.doi.org/10.1007/s13346-021-01064-8

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