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Assessment of dermal bioavailability: predicting the input function for topical glucocorticoids using stratum corneum sampling
Predicting the dermal bioavailability of topically delivered drugs is challenging. In this work, minimally invasive stratum corneum (SC) sampling was used to quantify the delivery of betamethasone valerate (BMV) into the viable skin. Betnovate® cream (0.1% w/w BMV) was applied at three doses (2, 5,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888398/ https://www.ncbi.nlm.nih.gov/pubmed/34599470 http://dx.doi.org/10.1007/s13346-021-01064-8 |