Triptolide Shows High Sensitivity and Low Toxicity Against Acute Myeloid Leukemia Cell Lines Through Inhibiting WSTF-RNAPII Complex

Triptolide exhibits superior and broad-spectrum antitumor activity. However, the narrow safety window caused by the toxicity of triptolide limits its clinical applications. Although several characterized targets for triptolide are reported, the association between triptolide and its targets in cance...

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Detalles Bibliográficos
Autores principales: Kang, Di, Liu, Yan, Song, Yi, Fang, Bingqian, Zhang, Qichun, Hu, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888427/
https://www.ncbi.nlm.nih.gov/pubmed/35251980
http://dx.doi.org/10.3389/fonc.2022.811850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888427/
https://www.ncbi.nlm.nih.gov/pubmed/35251980
http://dx.doi.org/10.3389/fonc.2022.811850

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