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Equipping Coiled-Coil Peptide Dimers With Furan Warheads Reveals Novel Cross-Link Partners

Using a coiled-coil peptide dimer as a model system to explore furan reactivity, we describe novel cross-link partners of furan warheads for site-specific cross-linking. We demonstrate that replacement of weak interhelical ionic contacts with a furan moiety and its potential cross-link partner affor...

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Detalles Bibliográficos
Autores principales:	Miret-Casals, Laia, Van De Putte, Sander, Aerssens, Dorien, Diharce, Julien, Bonnet, Pascal, Madder, Annemieke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888431/ https://www.ncbi.nlm.nih.gov/pubmed/35252125 http://dx.doi.org/10.3389/fchem.2021.799706

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