A Simplified SARS-CoV-2 Mouse Model Demonstrates Protection by an Oral Replicon-Based mRNA Vaccine

A mouse model of SARS-CoV-2 that can be developed in any molecular biology lab with standard facilities will be valuable in evaluating drugs and vaccines. Here we present a simplified SARS-CoV-2 mouse model exploiting the rapid adenoviral purification method. Mice that are sensitive to SARS-CoV-2 in...

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Detalles Bibliográficos
Autores principales: Jawalagatti, Vijayakumar, Kirthika, Perumalraja, Hewawaduge, Chamith, Park, Ji-Young, Yang, Myeon-Sik, Oh, Byungkwan, So, Mi Young, Kim, Bumseok, Lee, John Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888445/
https://www.ncbi.nlm.nih.gov/pubmed/35250985
http://dx.doi.org/10.3389/fimmu.2022.811802

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888445/
https://www.ncbi.nlm.nih.gov/pubmed/35250985
http://dx.doi.org/10.3389/fimmu.2022.811802

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