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A Simplified SARS-CoV-2 Mouse Model Demonstrates Protection by an Oral Replicon-Based mRNA Vaccine

A mouse model of SARS-CoV-2 that can be developed in any molecular biology lab with standard facilities will be valuable in evaluating drugs and vaccines. Here we present a simplified SARS-CoV-2 mouse model exploiting the rapid adenoviral purification method. Mice that are sensitive to SARS-CoV-2 in...

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Detalles Bibliográficos
Autores principales:	Jawalagatti, Vijayakumar, Kirthika, Perumalraja, Hewawaduge, Chamith, Park, Ji-Young, Yang, Myeon-Sik, Oh, Byungkwan, So, Mi Young, Kim, Bumseok, Lee, John Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888445/ https://www.ncbi.nlm.nih.gov/pubmed/35250985 http://dx.doi.org/10.3389/fimmu.2022.811802

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