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RGS3L allows for an M(2) muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes

The role and outcome of the muscarinic M(2) acetylcholine receptor (M(2)R) signaling in healthy and diseased cardiomyocytes is still a matter of debate. Here, we report that the long isoform of the regulator of G protein signaling 3 (RGS3L) functions as a switch in the muscarinic signaling, most lik...

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Detalles Bibliográficos
Autores principales: Levay, Magdolna K., Krobert, Kurt A., Vogt, Andreas, Ahmad, Atif, Jungmann, Andreas, Neuber, Christiane, Pasch, Sebastian, Hansen, Arne, Müller, Oliver J., Lutz, Susanne, Wieland, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888479/
https://www.ncbi.nlm.nih.gov/pubmed/35230541
http://dx.doi.org/10.1007/s00395-022-00915-w