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Impact of KRAS, BRAF and microsatellite instability status after cytoreductive surgery and HIPEC in a national cohort of colorectal peritoneal metastasis patients

BACKGROUND: Patients with metastatic colorectal cancer (mCRC) carrying BRAF (mutBRAF) or KRAS mutation (mutKRAS) have an inferior prognosis after liver or lung surgery, whereas the prognostic role in the context of peritoneal metastasis (PM) after cytoreductive surgery (CRS) and hyperthermic intrape...

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Detalles Bibliográficos
Autores principales: Larsen, S. G., Goscinski, M. A., Dueland, S., Steigen, S. E., Hofsli, E., Torgunrud, A., Lund-Iversen, M., Dagenborg, V. J., Flatmark, K., Sorbye, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888568/
https://www.ncbi.nlm.nih.gov/pubmed/34887523
http://dx.doi.org/10.1038/s41416-021-01620-6