CDH1 germline variants are enriched in patients with colorectal cancer, gastric cancer, and breast cancer

BACKGROUND AND AIMS: CDH1 germline variants have been linked to heritability in diffuse gastric (DGC) and lobular breast cancer (LBC). Studies have not yet assessed whether CDH1 is a cancer-susceptibility gene in other cancers. Herein, we mapped the landscape of pathogenic and likely pathogenic (P/L...

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Detalles Bibliográficos
Autores principales: Adib, Elio, El Zarif, Talal, Nassar, Amin H., Akl, Elie W., Abou Alaiwi, Sarah, Mouhieddine, Tarek H., Esplin, Edward D., Hatchell, Kathryn, Nielsen, Sarah M., Rana, Huma Q., Choueiri, Toni K., Kwiatkowski, David J., Sonpavde, Guru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888603/
https://www.ncbi.nlm.nih.gov/pubmed/34949788
http://dx.doi.org/10.1038/s41416-021-01673-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888603/
https://www.ncbi.nlm.nih.gov/pubmed/34949788
http://dx.doi.org/10.1038/s41416-021-01673-7

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