Transposase-CRISPR mediated targeted integration (TransCRISTI) in the human genome

Various methods have been used in targeted gene knock-in applications. CRISPR-based knock-in strategies based on homology-independent repair pathways such as CRISPR HITI have been shown to possess the best efficiency for gene knock-in in mammalian cells. However, these methods suffer from the probab...

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Detalles Bibliográficos
Autores principales: Rezazade Bazaz, Mahere, Ghahramani Seno, Mohammad M., Dehghani, Hesam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888626/
https://www.ncbi.nlm.nih.gov/pubmed/35232993
http://dx.doi.org/10.1038/s41598-022-07158-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888626/
https://www.ncbi.nlm.nih.gov/pubmed/35232993
http://dx.doi.org/10.1038/s41598-022-07158-8

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