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Crystal structure and catalytic mechanism of the MbnBC holoenzyme required for methanobactin biosynthesis

Methanobactins (Mbns) are a family of copper-binding peptides involved in copper uptake by methanotrophs, and are potential therapeutic agents for treating diseases characterized by disordered copper accumulation. Mbns are produced via modification of MbnA precursor peptides at cysteine residues cat...

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Detalles Bibliográficos
Autores principales: Dou, Chao, Long, Zhaolin, Li, Shoujie, Zhou, Dan, Jin, Ying, Zhang, Li, Zhang, Xuan, Zheng, Yanhui, Li, Lin, Zhu, Xiaofeng, Liu, Zheng, He, Siyu, Yan, Weizhu, Yang, Lulu, Xiong, Jie, Fu, Xianghui, Qi, Shiqian, Ren, Haiyan, Chen, She, Dai, Lunzhi, Wang, Binju, Cheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888699/
https://www.ncbi.nlm.nih.gov/pubmed/35110668
http://dx.doi.org/10.1038/s41422-022-00620-2