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Crystal structure and catalytic mechanism of the MbnBC holoenzyme required for methanobactin biosynthesis
Methanobactins (Mbns) are a family of copper-binding peptides involved in copper uptake by methanotrophs, and are potential therapeutic agents for treating diseases characterized by disordered copper accumulation. Mbns are produced via modification of MbnA precursor peptides at cysteine residues cat...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888699/ https://www.ncbi.nlm.nih.gov/pubmed/35110668 http://dx.doi.org/10.1038/s41422-022-00620-2 |