ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS–ERK–AP-1 T cell signaling-transcriptional axis

Immune stimulation fuels cell signaling-transcriptional programs inducing biological responses to eliminate virus-infected cells. Yet, retroviruses that integrate into host cell chromatin, such as HIV-1, co-opt these programs to switch between latent and reactivated states; however, the regulatory m...

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Detalles Bibliográficos
Autores principales: Ramirez, Nora-Guadalupe P., Lee, Jeon, Zheng, Yue, Li, Lianbo, Dennis, Bryce, Chen, Didi, Challa, Ashwini, Planelles, Vicente, Westover, Kenneth D., Alto, Neal M., D’Orso, Iván
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888757/
https://www.ncbi.nlm.nih.gov/pubmed/35232997
http://dx.doi.org/10.1038/s41467-022-28772-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888757/
https://www.ncbi.nlm.nih.gov/pubmed/35232997
http://dx.doi.org/10.1038/s41467-022-28772-0

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