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Robust Mendelian randomization in the presence of residual population stratification, batch effects and horizontal pleiotropy
Mendelian Randomization (MR) studies are threatened by population stratification, batch effects, and horizontal pleiotropy. Although a variety of methods have been proposed to mitigate those problems, residual biases may still remain, leading to highly statistically significant false positives in la...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888767/ https://www.ncbi.nlm.nih.gov/pubmed/35232963 http://dx.doi.org/10.1038/s41467-022-28553-9 |