Presentation of antigen on extracellular vesicles using transmembrane domains from viral glycoproteins for enhanced immunogenicity

A vaccine antigen, when launched as DNA or RNA, can be presented in various forms, including intracellular, secreted, membrane‐bound, or on extracellular vesicles (EVs). Whether an antigen in one or more of these forms is superior in immune induction remains unclear. In this study, we used GFP as a...

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Detalles Bibliográficos
Autores principales: Hu, Kai, McKay, Paul F., Samnuan, Karnyart, Najer, Adrian, Blakney, Anna K., Che, Junyi, O'Driscoll, Gwen, Cihova, Martina, Stevens, Molly M., Shattock, Robin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888812/
https://www.ncbi.nlm.nih.gov/pubmed/35233930
http://dx.doi.org/10.1002/jev2.12199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888812/
https://www.ncbi.nlm.nih.gov/pubmed/35233930
http://dx.doi.org/10.1002/jev2.12199

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