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Presentation of antigen on extracellular vesicles using transmembrane domains from viral glycoproteins for enhanced immunogenicity
A vaccine antigen, when launched as DNA or RNA, can be presented in various forms, including intracellular, secreted, membrane‐bound, or on extracellular vesicles (EVs). Whether an antigen in one or more of these forms is superior in immune induction remains unclear. In this study, we used GFP as a...
Autores principales: | Hu, Kai, McKay, Paul F., Samnuan, Karnyart, Najer, Adrian, Blakney, Anna K., Che, Junyi, O'Driscoll, Gwen, Cihova, Martina, Stevens, Molly M., Shattock, Robin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888812/ https://www.ncbi.nlm.nih.gov/pubmed/35233930 http://dx.doi.org/10.1002/jev2.12199 |
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