Loss of Function of mtHsp70 Chaperone Variants Leads to Mitochondrial Dysfunction in Congenital Sideroblastic Anemia

Congenital Sideroblastic Anemias (CSA) is a group of rare genetic disorders characterized by the abnormal accumulation of iron in erythrocyte precursors. A common hallmark underlying these pathological conditions is mitochondrial dysfunction due to altered protein homeostasis, heme biosynthesis, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Vishwanathan, Vinaya, D’Silva, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888832/
https://www.ncbi.nlm.nih.gov/pubmed/35252210
http://dx.doi.org/10.3389/fcell.2022.847045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888832/
https://www.ncbi.nlm.nih.gov/pubmed/35252210
http://dx.doi.org/10.3389/fcell.2022.847045

Ejemplares similares