Inhibition of the NLRP3 Inflammasome Activation by Manoalide Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis

The activation of NLRP3 inflammasome leads to cell pyroptosis and inflammatory cytokines secretion and gets involved in the development of many diseases, such as neuroinflammation and metabolic syndrome, but the drugs targeting NLRP3 are not clinically available for now. Through screening the small...

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Detalles Bibliográficos
Autores principales: Li, Cong, Lin, Hualong, He, Hongbin, Ma, Ming, Jiang, Wei, Zhou, Rongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888861/
https://www.ncbi.nlm.nih.gov/pubmed/35252186
http://dx.doi.org/10.3389/fcell.2022.822236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888861/
https://www.ncbi.nlm.nih.gov/pubmed/35252186
http://dx.doi.org/10.3389/fcell.2022.822236

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