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Fusion Gene Detection Using Whole-Exome Sequencing Data in Cancer Patients

Several fusion genes are directly involved in the initiation and progression of cancers. Numerous bioinformatics tools have been developed to detect fusion events, but they are mainly based on RNA-seq data. The whole-exome sequencing (WES) represents a powerful technology that is widely used for dis...

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Detalles Bibliográficos
Autores principales: Deng, Wenjiang, Murugan, Sarath, Lindberg, Johan, Chellappa, Venkatesh, Shen, Xia, Pawitan, Yudi, Vu, Trung Nghia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888970/
https://www.ncbi.nlm.nih.gov/pubmed/35251131
http://dx.doi.org/10.3389/fgene.2022.820493