The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions

BACKGROUND: Advanced maternal age is associated with decreased oocyte quantity and quality as well as uterine and placental dysfunctions. These changes lead to infertility, pregnancy complications and birth defects in the offspring. As the mean age of giving birth is increasing worldwide, prevention...

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Detalles Bibliográficos
Autores principales: Secomandi, Laura, Borghesan, Michela, Velarde, Michael, Demaria, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888999/
https://www.ncbi.nlm.nih.gov/pubmed/34918084
http://dx.doi.org/10.1093/humupd/dmab038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8888999/
https://www.ncbi.nlm.nih.gov/pubmed/34918084
http://dx.doi.org/10.1093/humupd/dmab038

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