The Binding Mode to Orthosteric Sites and/or Exosites Underlies the Therapeutic Potential of Drugs Targeting Cannabinoid CB(2) Receptors

The classical terms agonists and antagonists for G protein coupled receptors (GPCRs) have often become misleading. Even the biased agonism concept does not describe all the possibilities already demonstrated for GPCRs. The cannabinoid CB(2) receptor (CB(2)R) emerged as a promising target for a varie...

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Detalles Bibliográficos
Autores principales: Franco, Rafael, Morales, Paula, Navarro, Gemma, Jagerovic, Nadine, Reyes-Resina, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889005/
https://www.ncbi.nlm.nih.gov/pubmed/35250601
http://dx.doi.org/10.3389/fphar.2022.852631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889005/
https://www.ncbi.nlm.nih.gov/pubmed/35250601
http://dx.doi.org/10.3389/fphar.2022.852631

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