Deletion of Vhl in Dmp1-Expressing Cells Causes Microenvironmental Impairment of B Cell Lymphopoiesis

The contributions of skeletal cells to the processes of B cell development in the bone marrow (BM) have not been completely described. The von-Hippel Lindau protein (VHL) plays a key role in cellular responses to hypoxia. Previous work showed that Dmp1-Cre;Vhl conditional knockout mice (VhlcKO), whi...

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Detalles Bibliográficos
Autores principales: Chicana, Betsabel, Abbasizadeh, Nastaran, Burns, Christian, Taglinao, Hanna, Spencer, Joel A., Manilay, Jennifer O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889104/
https://www.ncbi.nlm.nih.gov/pubmed/35250971
http://dx.doi.org/10.3389/fimmu.2022.780945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889104/
https://www.ncbi.nlm.nih.gov/pubmed/35250971
http://dx.doi.org/10.3389/fimmu.2022.780945

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