A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection

Despite significant research efforts, treatment options for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain limited. This is due in part to a lack of therapeutics that increase host defense to the virus. Replication of SARS-CoV-2 in lung tissue is associated with marked infiltrat...

Descripción completa

Detalles Bibliográficos
Autores principales: Rocha, Savannah M., Fagre, Anna C., Latham, Amanda S., Cummings, Jason E., Aboellail, Tawfik A., Reigan, Philip, Aldaz, Devin A., McDermott, Casey P., Popichak, Katriana A., Kading, Rebekah C., Schountz, Tony, Theise, Neil D., Slayden, Richard A., Tjalkens, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889105/
https://www.ncbi.nlm.nih.gov/pubmed/35250984
http://dx.doi.org/10.3389/fimmu.2022.811430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889105/
https://www.ncbi.nlm.nih.gov/pubmed/35250984
http://dx.doi.org/10.3389/fimmu.2022.811430

Ejemplares similares