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Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus
BACKGROUND: Plasma extracellular vesicles (pEV) can harbor a diverse array of factors including active proteases and the amyloid-precursor-protein (APP) cleavage product Aβ, involved in plaque formation in Alzheimer`s diseases (AD). A potential role of such vesicles in AD pathology is unexplored. ME...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889140/ https://www.ncbi.nlm.nih.gov/pubmed/35220044 http://dx.doi.org/10.1016/j.ebiom.2022.103903 |