Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus

BACKGROUND: Plasma extracellular vesicles (pEV) can harbor a diverse array of factors including active proteases and the amyloid-precursor-protein (APP) cleavage product Aβ, involved in plaque formation in Alzheimer`s diseases (AD). A potential role of such vesicles in AD pathology is unexplored. ME...

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Detalles Bibliográficos
Autores principales: Lee, Jung-Hyun, Ostalecki, Christian, Oberstein, Timo, Schierer, Stefan, Zinser, Elisabeth, Eberhardt, Martin, Blume, Katja, Plosnita, Bianca, Stich, Lena, Bruns, Heiko, Coras, Roland, Vera-Gonzales, Julio, Maler, Manuel, Baur, Andreas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889140/
https://www.ncbi.nlm.nih.gov/pubmed/35220044
http://dx.doi.org/10.1016/j.ebiom.2022.103903

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