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A network-based computational and experimental framework for repurposing compounds toward the treatment of non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is among the most common liver pathologies, however, none approved condition-specific therapy yet exists. The present study introduces a drug repositioning (DR) approach that combines in vitro steatosis models with a network-based computational platform, con...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889147/ https://www.ncbi.nlm.nih.gov/pubmed/35252807 http://dx.doi.org/10.1016/j.isci.2022.103890 |