A network-based computational and experimental framework for repurposing compounds toward the treatment of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is among the most common liver pathologies, however, none approved condition-specific therapy yet exists. The present study introduces a drug repositioning (DR) approach that combines in vitro steatosis models with a network-based computational platform, con...

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Detalles Bibliográficos
Autores principales: Zareifi, Danae Stella, Chaliotis, Odysseas, Chala, Nafsika, Meimetis, Nikos, Sofotasiou, Maria, Zeakis, Konstantinos, Pantiora, Eirini, Vezakis, Antonis, Matsopoulos, George K., Fragulidis, Georgios, Alexopoulos, Leonidas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889147/
https://www.ncbi.nlm.nih.gov/pubmed/35252807
http://dx.doi.org/10.1016/j.isci.2022.103890

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