Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics

Non-clinical models to study metabolism including animal models and cell assays are often limited in terms of species translatability and predictability of human biology. This field urgently requires a push towards more physiologically accurate recapitulations of drug interactions and disease progre...

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Detalles Bibliográficos
Autores principales: Shroff, Tanvi, Aina, Kehinde, Maass, Christian, Cipriano, Madalena, Lambrecht, Joeri, Tacke, Frank, Mosig, Alexander, Loskill, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889168/
https://www.ncbi.nlm.nih.gov/pubmed/35232251
http://dx.doi.org/10.1098/rsob.210333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889168/
https://www.ncbi.nlm.nih.gov/pubmed/35232251
http://dx.doi.org/10.1098/rsob.210333

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