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Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics
Non-clinical models to study metabolism including animal models and cell assays are often limited in terms of species translatability and predictability of human biology. This field urgently requires a push towards more physiologically accurate recapitulations of drug interactions and disease progre...
Autores principales: | Shroff, Tanvi, Aina, Kehinde, Maass, Christian, Cipriano, Madalena, Lambrecht, Joeri, Tacke, Frank, Mosig, Alexander, Loskill, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889168/ https://www.ncbi.nlm.nih.gov/pubmed/35232251 http://dx.doi.org/10.1098/rsob.210333 |
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