Blood PD-1(+)TFh and CTLA-4(+)CD4(+) T cells predict remission after CTLA-4Ig treatment in early rheumatoid arthritis

OBJECTIVE: Treatment with CTLA-4Ig blocks T-cell activation and is clinically effective in RA. However, it is unknown if specific CD4(+) T-cell subsets in blood at baseline predict remission after CTLA-4Ig, or other biological treatments with different modes of action, and how treatment affects CD4(...

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Detalles Bibliográficos
Autores principales: Aldridge, Jonathan, Andersson, Kerstin, Gjertsson, Inger, Hultgård Ekwall, Anna-Karin, Hallström, Magnus, van Vollenhoven, Ronald, Lundell, Anna-Carin, Rudin, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889294/
https://www.ncbi.nlm.nih.gov/pubmed/34009274
http://dx.doi.org/10.1093/rheumatology/keab454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889294/
https://www.ncbi.nlm.nih.gov/pubmed/34009274
http://dx.doi.org/10.1093/rheumatology/keab454

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