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Sec23a inhibits the self-renewal of melanoma cancer stem cells via inactivation of ER-phagy

BACKGROUND: The genesis and developments of solid tumors, analogous to the renewal of healthy tissues, are driven by a subpopulation of dedicated stem cells, known as cancer stem cells (CSCs), that exhibit long-term clonal repopulation and self-renewal capacity. CSCs may regulate tumor initiation, g...

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Detalles Bibliográficos
Autores principales: Sun, Zhiwei, Liu, Doudou, Zeng, Bin, Zhao, Qiting, Li, Xiaoshuang, Chen, Hao, Wang, Jianyu, Rosie Xing, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889648/
https://www.ncbi.nlm.nih.gov/pubmed/35236368
http://dx.doi.org/10.1186/s12964-022-00827-1