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Sec23a inhibits the self-renewal of melanoma cancer stem cells via inactivation of ER-phagy
BACKGROUND: The genesis and developments of solid tumors, analogous to the renewal of healthy tissues, are driven by a subpopulation of dedicated stem cells, known as cancer stem cells (CSCs), that exhibit long-term clonal repopulation and self-renewal capacity. CSCs may regulate tumor initiation, g...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889648/ https://www.ncbi.nlm.nih.gov/pubmed/35236368 http://dx.doi.org/10.1186/s12964-022-00827-1 |