Partial p53 reactivation is sufficient to induce cancer regression

BACKGROUND: Impaired p53 function is one of the central molecular features of a tumor cell and even a partial reduction in p53 activity can increase the cancer risk in mice and men. From a therapeutic perspective it is noteworthy that tumor cells often become addicted to the absence of p53 providing...

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Detalles Bibliográficos
Autores principales: Klimovich, Boris, Meyer, Laura, Merle, Nastasja, Neumann, Michelle, König, Alexander M., Ananikidis, Nikolaos, Keber, Corinna U., Elmshäuser, Sabrina, Timofeev, Oleg, Stiewe, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889716/
https://www.ncbi.nlm.nih.gov/pubmed/35232479
http://dx.doi.org/10.1186/s13046-022-02269-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889716/
https://www.ncbi.nlm.nih.gov/pubmed/35232479
http://dx.doi.org/10.1186/s13046-022-02269-6

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