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Increased BMSC exosomal miR-140-3p alleviates bone degradation and promotes bone restoration by targeting Plxnb1 in diabetic rats

BACKGROUND: Diabetes mellitus (DM) is considered to be an important factor for bone degeneration disorders such as bone defect nonunion, which is characterized by physical disability and tremendous economy cost to families and society. Exosomal miRNAs of BMSCs have been reported to participate in os...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Liu, Xuanchen, Tang, Zhen, Wei, Xinghui, Dong, Hui, Liu, Yichao, Wu, Hao, Wu, Zhigang, Li, Xiaokang, Ma, Xue, Guo, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889728/
https://www.ncbi.nlm.nih.gov/pubmed/35236339
http://dx.doi.org/10.1186/s12951-022-01267-2