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Letrozole protects against cadmium-induced inhibition of spermatogenesis via LHCGR and Hsd3b6 to activate testosterone synthesis in mice

The heavy metal cadmium is proposed to be one of the environmental endocrine disruptors of spermatogenesis. Cadmium-induced inhibition of spermatogenesis is associated with a hormone secretion disorder. Letrozole is an aromatase inhibitor that increases peripheral androgen levels and stimulates sper...

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Detalles Bibliográficos
Autores principales: Yao, Yao, Wan, Yangyang, Shi, Xiaoyun, Guo, Lan, Jiang, Hui, Zhang, Xiansheng, Xu, Bo, Hua, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889770/
https://www.ncbi.nlm.nih.gov/pubmed/35236366
http://dx.doi.org/10.1186/s12958-022-00915-4