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Letrozole protects against cadmium-induced inhibition of spermatogenesis via LHCGR and Hsd3b6 to activate testosterone synthesis in mice
The heavy metal cadmium is proposed to be one of the environmental endocrine disruptors of spermatogenesis. Cadmium-induced inhibition of spermatogenesis is associated with a hormone secretion disorder. Letrozole is an aromatase inhibitor that increases peripheral androgen levels and stimulates sper...
Autores principales: | Yao, Yao, Wan, Yangyang, Shi, Xiaoyun, Guo, Lan, Jiang, Hui, Zhang, Xiansheng, Xu, Bo, Hua, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889770/ https://www.ncbi.nlm.nih.gov/pubmed/35236366 http://dx.doi.org/10.1186/s12958-022-00915-4 |
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