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Impact of the KIT/PDGFRA genotype on prognosis in imatinib‐naïve Japanese patients with gastrointestinal stromal tumor

BACKGROUND: Most gastrointestinal stromal tumors (GIST) harbor a mutation in KIT or platelet‐derived growth factor receptor alfa (PDGFRA). Although genotyping is a useful predictive marker of tyrosine kinase inhibitors, whether it can predict prognosis remains controversial. METHODS: Data on 402 pat...

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Detalles Bibliográficos
Autores principales: Cho, Haruhiko, Nishida, Toshirou, Takahashi, Tsuyoshi, Masuzawa, Toru, Hirota, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889858/
https://www.ncbi.nlm.nih.gov/pubmed/35261949
http://dx.doi.org/10.1002/ags3.12527