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TorsinA folding and N-linked glycosylation are sensitive to redox homeostasis

The Endoplasmic Reticulum (ER) is responsible for the folding and post-translational modification of secretory proteins, as well as for triaging misfolded proteins. During folding, there is a complex yet only partially understood interplay between disulfide bond formation, which is an enzyme catalyz...

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Detalles Bibliográficos
Autores principales: Honer, Jonas, Niemeyer, Katie M., Fercher, Christian, Tissera, Ana L. Diez, Jaberolansar, Noushin, Jafrani, Yohaann M.A., Zhou, Chun, Caramelo, Julio J., Shewan, Annette M., Schulz, Benjamin L., Brodsky, Jeffrey L., Zacchi, Lucía F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889903/
https://www.ncbi.nlm.nih.gov/pubmed/34062155
http://dx.doi.org/10.1016/j.bbamcr.2021.119073