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Glypican-3: A Novel and Promising Target for the Treatment of Hepatocellular Carcinoma

Glypican-3 (GPC3) is a membrane-associated proteoglycan that is specifically up-regulated in hepatocellular carcinoma (HCC) although rarely or not expressed in normal liver tissues, making it a perfect diagnostic and treatment target for HCC. Several GPC3-based clinical trials are ongoing and recent...

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Detalles Bibliográficos
Autores principales: Zheng, Xiufeng, Liu, Xun, Lei, Yanna, Wang, Gang, Liu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8889910/
https://www.ncbi.nlm.nih.gov/pubmed/35251989
http://dx.doi.org/10.3389/fonc.2022.824208