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Tumor suppressor pathways shape EGFR-driven lung tumor progression and response to treatment

In vivo modeling combined with CRISPR/Cas9-mediated somatic genome editing has contributed to elucidating the functional importance of specific genetic alterations in human tumors. Our recent work uncovered tumor suppressor pathways that affect EGFR-driven lung tumor growth and sensitivity to tyrosi...

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Detalles Bibliográficos
Autores principales: Foggetti, Giorgia, Li, Chuan, Cai, Hongchen, Petrov, Dmitri A., Winslow, Monte M., Politi, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890383/
https://www.ncbi.nlm.nih.gov/pubmed/35252550
http://dx.doi.org/10.1080/23723556.2021.1994328