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Upregulation of antimicrobial peptide expression in slc26a3-/- mice with colonic dysbiosis and barrier defect

Genetic defects in SLC26A3 (DRA), an intestinal Cl(−)/HCO(3)(−) exchanger, result in congenital chloride diarrhea (CLD), marked by lifelong acidic diarrhea and a high risk of inflammatory bowel disease. Slc26a3(−/−) mice serve as a model to understand the pathophysiology of CLD and search for treatm...

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Detalles Bibliográficos
Autores principales:	Kini, Archana, Zhao, Bei, Basic, Marijana, Roy, Urmi, Iljazovic, Aida, Odak, Ivan, Ye, Zhenghao, Riederer, Brigitte, Di Stefano, Gabriella, Römermann, Dorothee, Koenecke, Christian, Bleich, André, Strowig, Till, Seidler, Ursula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890434/ https://www.ncbi.nlm.nih.gov/pubmed/35230892 http://dx.doi.org/10.1080/19490976.2022.2041943

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