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A novel role for nucleolin in splice site selection

Latent 5ʹ splice sites, not normally used, are highly abundant in human introns, but are activated under stress and in cancer, generating thousands of nonsense mRNAs. A previously proposed mechanism to suppress latent splicing was shown to be independent of NMD, with a pivotal role for initiator-tRN...

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Detalles Bibliográficos
Autores principales: Shefer, Kinneret, Boulos, Ayub, Gotea, Valer, Arafat, Maram, Ben Chaim, Yair, Muharram, Aya, Isaac, Sara, Eden, Amir, Sperling, Joseph, Elnitski, Laura, Sperling, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890436/
https://www.ncbi.nlm.nih.gov/pubmed/35220879
http://dx.doi.org/10.1080/15476286.2021.2020455