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IL-10 Indirectly Downregulates IL-4–Induced IgE Production by Human B Cells

Controlled allergic disease is associated with decreased allergen-specific IgE and increased allergen-specific IgG4. Although IL-10 has been shown to contribute to these changes, the underlying mechanisms are largely unknown. This study explored how IL-10 differentially regulates human IgE and IgG4...

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Detalles Bibliográficos
Autores principales: Lin, Adora A., Freeman, Alexandra F., Nutman, Thomas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890443/
https://www.ncbi.nlm.nih.gov/pubmed/31026808
http://dx.doi.org/10.4049/immunohorizons.1800076