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Dynamic RNA Fitness Landscapes of a Group I Ribozyme during Changes to the Experimental Environment

Fitness landscapes of protein and RNA molecules can be studied experimentally using high-throughput techniques to measure the functional effects of numerous combinations of mutations. The rugged topography of these molecular fitness landscapes is important for understanding and predicting natural an...

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Detalles Bibliográficos
Autores principales: Peri, Gianluca, Gibard, Clémentine, Shults, Nicholas H, Crossin, Kent, Hayden, Eric J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890501/
https://www.ncbi.nlm.nih.gov/pubmed/35020916
http://dx.doi.org/10.1093/molbev/msab373