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Dynamic RNA Fitness Landscapes of a Group I Ribozyme during Changes to the Experimental Environment
Fitness landscapes of protein and RNA molecules can be studied experimentally using high-throughput techniques to measure the functional effects of numerous combinations of mutations. The rugged topography of these molecular fitness landscapes is important for understanding and predicting natural an...
Autores principales: | Peri, Gianluca, Gibard, Clémentine, Shults, Nicholas H, Crossin, Kent, Hayden, Eric J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890501/ https://www.ncbi.nlm.nih.gov/pubmed/35020916 http://dx.doi.org/10.1093/molbev/msab373 |
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