Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance

Olorofim (F901318) is a new antifungal currently under clinical development that shows both in vitro and in vivo activity against a number of filamentous fungi including Aspergillus fumigatus. In this study, we screened A. fumigatus isolates for intrinsic olorofim-resistant A. fumigatus and evaluate...

Descripción completa

Detalles Bibliográficos
Autores principales: Buil, Jochem B., Oliver, Jason D., Law, Derek, Baltussen, Tim, Zoll, Jan, Hokken, Margriet W. J., Tehupeiory-Kooreman, Marlou, Melchers, Willem J. G., Birch, Mike, Verweij, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Antimicrobial Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890541/
https://www.ncbi.nlm.nih.gov/pubmed/35109772
http://dx.doi.org/10.1080/22221751.2022.2034485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890541/
https://www.ncbi.nlm.nih.gov/pubmed/35109772
http://dx.doi.org/10.1080/22221751.2022.2034485

Ejemplares similares