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Resistance profiling of Aspergillus fumigatus to olorofim indicates absence of intrinsic resistance and unveils the molecular mechanisms of acquired olorofim resistance

Olorofim (F901318) is a new antifungal currently under clinical development that shows both in vitro and in vivo activity against a number of filamentous fungi including Aspergillus fumigatus. In this study, we screened A. fumigatus isolates for intrinsic olorofim-resistant A. fumigatus and evaluate...

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Detalles Bibliográficos
Autores principales:	Buil, Jochem B., Oliver, Jason D., Law, Derek, Baltussen, Tim, Zoll, Jan, Hokken, Margriet W. J., Tehupeiory-Kooreman, Marlou, Melchers, Willem J. G., Birch, Mike, Verweij, Paul E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Antimicrobial Agents
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890541/ https://www.ncbi.nlm.nih.gov/pubmed/35109772 http://dx.doi.org/10.1080/22221751.2022.2034485

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