Discovery of novel paeonol-based derivatives against skin inflammation in vitro and in vivo

T-LAK-cell-originated protein kinase (TOPK), a novel member of the mitogen-activated protein kinase family, is considered an effective therapeutic target for skin inflammation. In this study, a series (A − D) of paeonol derivatives was designed and synthesised using a fragment growing approach, and...

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Detalles Bibliográficos
Autores principales: Wu, Jing, Zhu, Ren De, Cao, Guo Min, Du, Jun Cheng, Liu, Xin, Diao, Liang Zhuo, Zhang, Zhao Yan, Hu, Yang Sheng, Liu, Xin Hua, Shi, Jing Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890542/
https://www.ncbi.nlm.nih.gov/pubmed/35220836
http://dx.doi.org/10.1080/14756366.2022.2043852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890542/
https://www.ncbi.nlm.nih.gov/pubmed/35220836
http://dx.doi.org/10.1080/14756366.2022.2043852

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