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Protective role of crocin against sepsis-induced injury in the liver, kidney and lungs via inhibition of p38 MAPK/NF-κB and Bax/Bcl-2 signalling pathways

CONTEXT: Crocin has been reported to have multiple bioactivities. However, the effect of crocin administration on caecal ligation and puncture (CLP)-induced sepsis remains unknown. OBJECTIVE: We investigated the effects of crocin on CLP-induced sepsis in mice and the underlying mechanism of action....

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Detalles Bibliográficos
Autores principales: Gao, Jun, Zhao, Feng, Yi, Shaona, Li, Shuhang, Zhu, Aiqing, Tang, Yingxiu, Li, Aiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8890572/
https://www.ncbi.nlm.nih.gov/pubmed/35225146
http://dx.doi.org/10.1080/13880209.2022.2042328